Search on:
BRAIN-SPECIFIC 24S-HYDROXYLASE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Cholesterol 24-Hydroxylase
Descriptor
Spanish
:
Colesterol 24-Hidroxilasa
Descriptor
Portuguese
:
Colesterol 24-Hidroxilase
Synonyms
English
:
5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
Brain-Specific 24S-Hydroxylase
CYP46A1
Cholestane Tetrol 24-Hydroxylase
Cytochrome P450 46A1
Brain Specific 24S Hydroxylase
Cholestane Tetrol 24 Hydroxylase
Cholesterol 24 Hydroxylase
Tree Number:
D08.244.453.875.500
D08.244.453.915.025
D08.811.682.690.708.170.497.500
D08.811.682.690.708.170.915.025
D12.776.422.220.453.875.500
D12.776.422.220.453.915.025
Definition
English
:
A steroid hydroxylase that functions in
CHOLESTEROL
homeostasis
in the brain. It converts
cholesterol
into 24S-hydroxycholesterol, which is transported over the
BLOOD-BRAIN BARRIER
more rapidly than unmetabolized
cholesterol.
History Note
English
:
2017 (1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56451
Unique Identifier:
D000072556
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS